Additional information Active substance Metformin Hydrochloride Formula C4H11N5В·HCl Side effects Gastrointestinal disturbances (such as diarrhea, nausea, vomiting), vitamin B12 deficiency, lactic acidosis (rare but serious) Effects Reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization Dosage (sports) Not typically prescribed for sports enhancement Dosage (medical) Typically starting at 500 mg twice a day or 850 mg once a day, up to a maximum of 2000-2550 mg per day depending on the patient's response and tolerance Half-life Approximately 6.2 hours Main action Antihyperglycemic agent Substance class Biguanide Chemical name Metformin hydrochloride Storage conditions Store at room temperature away from moisture and light FORM 60 tabs x 500 mg/tab Trade name Glucophage, Glumetza, others Blood pressure Can lead to a slight reduction in blood pressure Also known as Metformin HCL Lab Test Monitoring of renal function and serum electrolytes recommended Hepatotoxicity Low risk Water Retention Does not cause significant water retention Use in sports Not commonly used as a performance enhancer, but some athletes might use it for weight management Manufacturer MERCK
